Jacqueline du Pré was an astounding English Cellist. She achieved high performance at a young age before she lost her abilities (at 28) to the loss of myelin[*] due to multiple sclerosis (MS). At first she lost sensation in her fingers so she used her visual senses to coordinate her fingers while playing.
She is most famous for her iconic recording of Elgar’s Cello Concerto in E Minor.
Here’s a short version of the concerto followed by a playlist of the full concerto